The Hyatt Regency Johannesburg is located in the Rosebank suburb of the city. This places it close to the business districts. There are also many social diversions to be found nearby. For shopping, the Firs Shopping Mall provides a wide selection of retailers from which one may choose. The Johannesburg International Airport provides an arrival point for guests of the Hyatt Regency Johannesburg.

There are 244 rooms for hire at the Hyatt Regency Johannesburg. Each room is decorated in African themes. The rooms include satellite television service, minibars, complimentary newspapers during the week and non-smoking options.

The Hyatt Regency Johannesburg contains a host of amenities suitable for those arriving on business or simply for pleasure. There is a fitness center at the hotel which includes a sauna and a steam room. There is a spa onsite which offers beauty treatments. Guests may also unwind in the bar. There is a restaurant onsite which specializes in Italian cuisine but which also serves a broad international menu.